NIPT
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NIPT
Non-invasive prenatal testing (NIPT) is a blood test performed as early as the 10th week of pregnancy to assess the risk of certain chromosomal conditions in the fetus by analyzing cell-free fetal DNA in the mother’s blood. It is highly sensitive, with detection rates exceeding 99% for Down syndrome (trisomy 21), and also detects trisomy 18 and trisomy 13 with high accuracy. NIPT can also assess the risk of some sex chromosome abnormalities and certain microdeletion syndromes, but it does not detect all possible genetic conditions or structural abnormalities. It is a screening test rather than a diagnostic one, meaning positive results typically require confirmatory testing such as amniocentesis or chorionic villus sampling (CVS).
How does NIPT work?
- A simple blood sample is taken from the mother.
- The blood contains fragments of DNA from the fetus, which can be analyzed to detect chromosomal abnormalities.
- NIPT is highly accurate for detecting conditions like Down syndrome, trisomy 18, and trisomy 13.
When is NIPT performed?
- NIPT can usually be done as early as 10 weeks of pregnancy.
What are the benefits of NIPT?
- It’s a non-invasive test, meaning it doesn’t involve any procedures that could harm the fetus.
- It’s highly accurate, especially for detecting Down syndrome.
- It can provide early information about the risk of chromosomal abnormalities, allowing parents to make informed decisions about their pregnancy.
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