Cordocentesis
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Cordocentesis
Cordocentesis, also known as percutaneous umbilical blood sampling (PUBS), is a prenatal diagnostic procedure that involves taking a blood sample from the umbilical cord. This procedure is typically performed after 18 weeks of pregnancy and is used to diagnose a variety of genetic and chromosomal disorders.
When is Cordocentesis Performed?
- High-Risk Pregnancies: When there is a high risk of genetic or chromosomal abnormalities.
- Rapid Diagnosis: When a quick diagnosis is needed for medical management.
- Other Conditions: May be used to diagnose blood disorders, infections, or metabolic diseases.
How is Cordocentesis Performed?
Ultrasound Guidance: Ultrasound is used to guide a thin needle through the mother’s abdomen and into the placenta.
Blood Sampling: A small amount of blood is extracted from the umbilical cord.
Analysis: The blood sample is then analyzed in a laboratory to detect any abnormalities.
What Information Does Cordocentesis Provide?
Chromosomal Abnormalities: Can diagnose conditions like Down syndrome, trisomy 18, and trisomy 13.
Genetic Disorders: Can detect genetic diseases such as cystic fibrosis and sickle cell anemia.
Blood Disorders: Can diagnose blood disorders like hemophilia and leukemia.
Infections: Can identify certain infections that may affect the fetus.
Risks Associated with Cordocentesis
- Miscarriage: There is a small risk of miscarriage following cordocentesis, typically less than 1%.
- Bleeding: There is a risk of bleeding from the puncture site.
- Infection: There is a very low risk of infection.
Important Note: Cordocentesis is a more invasive procedure compared to other prenatal diagnostic tests. It is typically recommended only in high-risk cases where the benefits outweigh the risks.
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